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| Product Name | SB 202190 |
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| Description | A highly selective, potent and cell-permeable inhibitor of p38 MAP kinase. Binds within the ATP pocket of the active kinase (Kd = 38 nM, as measured in recombinant human p38), and selectively inhibits the p38α and β isoforms (IC50 = 50 and 100 nM at SAPK2a/p38 and SAPK2b/p38β2 respectively). Promotes stability of naive human pluripotent stem cells in culture. Also available as part of the MAPK Inhibitor Tocriset™. Purity 99%. MW (observed): 331.35 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol |
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| Gene, Accession, CAS # | CAS: 152121-30-7 |
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| Catalog # | 1264/10 |
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| Order / More Info | SB 202190 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 12794003, 14691054, 15152046, 15687501, 16086034, 16595546, 16723500, 19723763, 19846725, 20724703, 21097523, 21547253, 21585337, 21685895, 22003401, 22415826, 22463935, 22683469, 23467095, 23497702, 23792643, 23968581, 24172903, 24555435, 24956278, 25775465, 25925867, 26115412, 26549644, 27663973, 28484457, 28570931, 29175508 |
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