产品详情 |
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Product Name | PA 1 dihydrochloride |
Description | Photoswitchable epithelial sodium channel (ENaC) blocker (IC50 values are 90 and 390 nM for αβγ and δβγENaCs, respectively, in the trans conformation). Switches conformation from cis to trans at 500 nm and trans to cis at 400 nm. Blocks ENaCs with greater efficacy in the cis conformation, in comparison to the trans conformation, in Xenopus oocytes and HEK293t cells. Partially blocks δβγENaCs in the trans conformation and exhibits near maximal block of δβγENaCs in the cis conformation. Amiloride derivative. Purity 98%. MW (observed): 482.75 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 3,5-Diamino-6-chloro-N-[imino[[4-(2-phenyldiazenyl)phenyl]amino]methyl]-2-pyrazinecarboxamide dihydrochloride |
Gene, Accession, CAS # | n/a |
Catalog # | 5463/10 |
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Order / More Info | PA 1 dihydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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