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| Product Name | A 438079 hydrochloride |
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| Description | Competitive P2X7 receptor antagonist (pIC50 = 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line). Devoid of activity at other P2 receptors (IC50 >> 10 μM). Possesses antinociceptive activity in models of neuropathic pain in vivo. Inhibits methamphetamine-induced microglial migration and phagocytosis in vitro. Purity 98%. MW (observed): 342.61 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-[[5-(2,3-Dichlorophenyl)-1H-tetrazol-1-yl]methyl]pyridine hydrochloride |
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| Gene, Accession, CAS # | CAS: 899431-18-6 |
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| Catalog # | 2972/10 |
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| Order / More Info | A 438079 hydrochloride from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 18987356, 20071520, 20382737, 20495003, 20878769, 20884646, 21262970, 21289095, 21381023, 21397667, 21505260, 21631954, 22022466, 22185840, 22383490, 22405772, 22506590, 22661222, 22753954, 22843620, 22984079, 23319734, 24048730, 24108003, 24163006, 24970925, 25127716, 25379376, 25445541, 25700737, 25752193, 25938443, 25998681, 26050734, 26552848, 26607222, 26877061, 27385779, 27932954, 29070054 |
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