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| Product Name | Ailanthone |
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| Description | Potent androgen receptor (AR) inhibitor (IC50 = 69 nM). Disrupts the AR-chaperone complex by binding p23 and blocking AR interaction with HSP90 causing UPS degradation of AR. Inhibits Huh7 cancer cell growth via G0/G1 cell cycle arrest and apoptosis in vitro and in vivo. Inhibits growth and metastasis of certain prostate cancer cell lines. Orally bioavailable. Purity 98%. MW (observed): 376.4 |
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| Size | 5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (1β,11β,12α)-11,20-Epoxy-1,11,12-trihydroxypicrasa-3,13(21)-diene-2,16-dione |
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| Gene, Accession, CAS # | CAS: 981-15-7 |
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| Catalog # | 6161/5 |
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| Price | |
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| Order / More Info | Ailanthone from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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