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| Product Name | Z-Guggulsterone |
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| Description | Broad spectrum steroid receptor ligand; mineralocorticoid, progesterone and glucocorticoid receptor antagonist (Ki values are 37, 224 and 252 nM respectively) and weak androgen receptor agonist (Ki = 315 nM). Induces apoptosis in prostate cancer cells and inhibits angiogenesis via suppression of the VEGF-VEGFR2-Akt signaling pathway. Exhibits antilipidemic activity via antagonism of the farnesoid X receptor (FXR) and displays antiseptic, antirheumatic and anti-inflammatory activity in vivo. More active isomer of guggulsterone (Cat. No. 2013). Purity 98%. MW (observed): 312.45 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (Z)-Pregna-4,17(20)-diene-3,16-dione |
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| Gene, Accession, CAS # | CAS: 39025-23-5 |
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| Catalog # | 3570/10 |
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| Order / More Info | Z-Guggulsterone from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 27006468 |
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| 产品资料 |
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