| 产品详情 |
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| Product Name | AEE 788 |
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| Description | Potent EGFR and VEGFR inhibitor (IC50 values are 2, 6, 59, 77, 160 and 330 nM for EGFR, ErbB2, VEGFR-1, VEGFR-2, ErbB4 and VEGFR-3 respectively). Also inhibits c-Abl, c-Fms and c-Src (IC50 values are 52, 60 and 61 nM respectively). Inhibits proliferation of EGFR and ErbB2 overexpressing cancer cell lines in vitro. Inhibits tumor xenograft growth and VEGF-induced angiogenesis in mice. Orally active. Purity 98%. MW (observed): 440.58 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
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| Gene, Accession, CAS # | CAS: 497839-62-0 |
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| Catalog # | 5318/10 |
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| Price | |
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| Order / More Info | AEE 788 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25823819 |
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| 产品资料 |
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