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| Product Name | HGF, Recombinant, Human, aa32-285 |
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| Description | Purity ~80% (SDS-PAGE). Hepatocyte growth factor (HGF) regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69kD alpha-chain and 34kD beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Source: Recombinant protein corresponding to aa32-285 from human HGF expressed in E.coli. Molecular Weight: ~29.8kD (255aa) Applications: Suitable for use in SDS-PAG |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | HGF, Recombinant, Human, aa32-285 (Hepatocyte Growth Factor Isoform 1 Preproprotein, Scatter Factor, DFNB39, F-TCF, HGFB, HPTA, SF, Hepatopoietin A) |
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| Gene, Accession, CAS # | Accession: NP_001010933 |
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| Catalog # | 218223 |
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| Order / More Info | HGF, Recombinant, Human, aa32-285 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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