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Product Name | AEG 3482 |
Description | Inhibitor of c-jun N-terminal kinase (JNK) signaling. Binds Hsp90 and facilitates HSF1 release, induces expression of Hsp70, which in turn blocks JNK activation and JNK-dependent apoptosis. Antiapoptotic; inhibits NGF withdrawal-induced death in SCG neurons (EC50 = 20 μM). Purity 99%. MW (observed): 280.33 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 6-Phenylimidazo[2,1-b]-1,3,4-thiadiazole-2-sulfonamide |
Gene, Accession, CAS # | CAS: 63735-71-7 |
Catalog # | 2651/10 |
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Order / More Info | AEG 3482 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 21829588, 27293988 |
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