产品详情 |
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Product Name | AEG 40730 dihydrochloride |
Description | IAP antagonist; binds to the BIR3 domain of cIAP1, cIAP2 and XIAP with nanomolar affinity. Reduces cIAP1, cIAP2 and XIAP protein levels in human breast cancer MDA-MB-231 cells. Induces apoptosis in combination with TNF, and potentiates TRAIL-mediated apoptosis in human colorectal carcinoma HCT 116 cells. Cell permeable. Purity 98%. MW (observed): 1120.06 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 222,Trifluoro-N-[[(2S)-1-(N-methyl-L-analyl-L-threonyl)-2-pyrrolidinyl]methyl]-N-(2-phenylethyl)acetamide, diethyl ether with 2,4-hexadiyne-1.6-diol dihydrochloride |
Gene, Accession, CAS # | n/a |
Catalog # | 5330/50 |
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Order / More Info | AEG 40730 dihydrochloride from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 24463573 |
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