| 产品详情 |
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| Product Name | HGF, Recombinant, Mouse (Hepatocyte Growth Factor, Scatter Factor, SF, Hepatopoietin, HPTA) |
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| Description | Purity ~95% (SDS-PAGE). HGF is a mesenchymally derived potent mitogen for mature parenchymal hepatocyte cells and acts as a growth factor for a broad spectrum of tissues and cell types. HGF signals through a transmembrane tyrosine kinase receptor known as MET. Activities of HGF include induction of cell proliferation, motility, morphogenesis, inhibition of cell growth, and enhancement of neuron survival. HGF is a crucial mitogen for liver regeneration processes, especially after partial hepatectomy and other liver injuries. Human and mouse HGF are cross-reactive. Mouse HGF is expressed as a linear 728aa polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of HGF, which consists of two polypeptide chains (alpha-chain and beta-chain) held by a single disulfide bond resulting in formation of a biologically active heterodimer. The alpha-chain consists of 463aa residues and four kringle domains. The beta-chain consists of 233aa |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Scatter Factor (SF), Hepatopoietin (HPTA) |
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| Gene, Accession, CAS # | HGF, Gene ID: 15234, SwissProt: Q08048 |
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| Catalog # | 219847 |
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| Order / More Info | HGF, Recombinant, Mouse (Hepatocyte Growth Factor, Scatter Factor, SF, Hepatopoietin, HPTA) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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