产品详情 |
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Product Name | ZCL 278 |
Description | Selective inhibitor of Cdc42. Targets the binding site of the Cdc42 guanine nucleotide exchange factor, intersectin (ITSN). Inhibits Cdc42-mediated cellular effects, including microspike formation in 3T3 fibroblasts and neuronal branching in primary neonatal cortical neurons. Also suppresses cell motility and migration in PC3 cells, without cytotoxic effects. Purity 95%. MW (observed): 584.89 |
Size | 50 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-(4-Bromo-2-chlorophenoxy)-N-[[[4-[[(4,6-dimethyl-2-pyrimidinyl)amino]sulfonyl]phenyl]amino]thioxomethyl]acetamide |
Gene, Accession, CAS # | CAS: 587841-73-4 |
Catalog # | 4794/50 |
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Order / More Info | ZCL 278 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 25814944, 26074769, 28122114, 28564597 |
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