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| Product Name | Macbecin I |
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| Description | Ansamycin antibiotic compound that inhibits Hsp90 activity (IC50 = 2 μM) by binding to the ATP-binding site. Exhibits antitumor and cytocidal activities (IC50 ~ 0.4 μM) by causing degradation of key oncogenic client proteins such as ErbB2 and cRaf1. Displays higher affinity and potency than geldanamycin (Cat. No. 1368). MW (observed): 558.67. |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (15R)-6,17-Didemethoxy-15-methoxy-6-methyl-11-O-methyl-geldanamycin |
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| Gene, Accession, CAS # | Gene ID: 3320, CAS: 73341-72-7 |
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| Catalog # | 3061/1 |
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| Price | |
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| Order / More Info | Macbecin I from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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