| 产品详情 |
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| Product Name | Maraviroc |
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| Description | Selective CCR5 antagonist; displays potent anti-HIV-1 activity. Prevents the interaction of HIV-1 gp120 and CCR5 (IC50 = 6.4 nM), inhibiting HIV-1 entry. Exhibits antinociceptive effects in a rat model of neuropathic pain. Also inhibits CCL3 (MIP-1α) binding to CCR5. Orally bioavailable. Purity 99%. MW (observed): 513.67 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4,4-Difluoro-N-{(1S)-3-[3-(3-isopropyl- 5-methyl-4H-1,2,4-triazol-4-yl)- 8-azabicyclo[3.2.1]oct-8-yl]-1- phenylpropyl}cyclohexanecarboxamide. UK-427857 |
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| Gene, Accession, CAS # | CAS: 376348-65-1 |
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| Catalog # | 3756/10 |
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| Order / More Info | Maraviroc from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 25712213, 26511387, 27117708, 29760499 |
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| 产品资料 |
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