产品详情 |
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Product Name | Maritoclax |
Description | Mcl-1 inhibitor; disrupts Mcl-1-Bim interaction and induces Mcl-1 proteasomal degradation. Exhibits no effect on Bcl-XL-Bim interaction. Selectively induces apoptosis in Mcl-1-dependent K562 leukemia cells. Sensitizes K562 and Raji cells to ABT-737-induced apoptosis. Purity 97%. MW (observed): 510.15 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1,1'-(4,4',5,5'-Tetrachloro[1,3'-bi-1H-pyrrole]-2,2'-diyl)bis[1-2-hydroxyphenyl)methanone |
Gene, Accession, CAS # | CAS: 1227962-62-0 |
Catalog # | 5368/10 |
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Order / More Info | Maritoclax from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 22311987 |
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