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| Product Name | 3-MATIDA |
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| Description | Potent metabotropic glutamate mGlu1 receptor antagonist (IC50 = 6.3 μM at rat mGlu1a). Displays ≥ 40-fold selectivity over other receptors: mGlu5, mGlu2, mGlu4a (IC50 > 300 μM), NMDA and AMPA (IC50 = 250 μM). Neuroprotective in cultured murine cortical cells and rat hippocampal slice cultures in vitro. Reduces the volume of ischemia-induced brain infarcts in rats following systemic administration in vivo. Purity 99%. MW (observed): 215.23 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | α-Amino-5-carboxy-3-methyl-2-thiopheneacetic acid |
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| Gene, Accession, CAS # | CAS: 518357-51-2 |
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| Catalog # | 2196/10 |
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| Order / More Info | 3-MATIDA from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 21753005 |
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