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Product Name | IL21, 30-162aa, Human, His-tag, Baculovirus (Bioactivity Validated) |
Description | Purity: > 85% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 20% glycerol.. IL21, also known as interleukin-21 isoform 1, is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumour responses. It has broad immunoregulatory activity and can modulate both humoral and cell-mediated responses. It is important in the regulation of haematopoiesis and immune responses, and can influence lymphocyte development. It is produced by activated T cells, and it influences proliferation of T and B cells and cytolytic activity of natural killer cells. It may be a critical factor in the control of persistent viral infections. It has a potential predicating significance for survival time in patients in the development of sporadic CRC. It binds to the IL-21R and can activate Janus kinase JAK1, JAK3, STAT1, and STAT3 in EDgamma-16 cells. Recombinant human IL21, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Size | 50ug, 10ug, |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Interleukin-21 isoform 1, IL21, CVID11, IL-21, Za11 |
Gene, Accession, CAS # | NP 068575 |
Catalog # | ATGP3802 |
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Order / More Info | IL21, 30-162aa, Human, His-tag, Baculovirus (Bioactivity Validated) from ATGen |
Product Specific References | n/a |
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