产品详情 |
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Product Name | MM 102 |
Description | Potent WDR5/MLL interaction inhibitor (IC50 = 2.4 nM). Inhibits MLL1 methyltransferase activity and MLL-1-induced HoxA9 and Meis-1 gene expression in leukemia cells expressing the MLL1-AF9 fusion gene. Also inhibits cell growth and induces apoptosis in leukemia cells harbouring MLL1 fusion proteins. Purity 98%. MW (observed): 783.83 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 1-[[(2S)-5-[(Aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[bis(4-fluorophenyl)methyl]-cyclopentanecarboxamide trifluoroacetate |
Gene, Accession, CAS # | CAS: 1883545-52-5 |
Catalog # | 5307/10 |
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Order / More Info | MM 102 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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