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| Product Name | IFITM1, Recombinant, Human, aa1-36, GST-Tag (Interferon-induced Transmembrane Protein 1) |
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| Description | Purity ~90% (SDS-PAGE). IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation. Source: Recombinant protein corresponding to aa1-36 from human IFITM1, fused to GST-T |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Dispanin subfamily A member 2a, DSPA2a Interferon-induced protein 17, Interferon-inducible protein 9-27 Leu-13 antigen, CD225 Dispanin subfamily A member 2a, DSPA 2a Interferon-induced protein 17 Interferon-inducible protein 9-27, Leu-13 antigen, CD225 |
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| Gene, Accession, CAS # | SwissProt: P13164 |
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| Catalog # | 373740 |
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| Order / More Info | IFITM1, Recombinant, Human, aa1-36, GST-Tag (Interferon-induced Transmembrane Protein 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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