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| Product Name | Interleukin 1 alpha, Recombinant, Human |
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| Description | Purity ≥ 98% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified. A soluble factor produced by monocytes, macrophages, and other cells which activates T-lymphocytes and potentiates their response to mitogens or antigens. IL-1 consists of two distinct forms, IL-1 alpha and IL-1 beta which perform the same functions but are distinct proteins. The synthesis of IL-1 can be induced by other cytokines including TNF-alpha, IFN-alpha, IFN-beta and IFN-g and also by bacterial endotoxins, viruses, mitogens, and antigens. In human skin fibroblasts IL1-alpha and TNF-alpha induce the synthesis of IL1-beta. In pheochromocytoma cells, NGF induces the synthesis of IL1. Recombinant Human IL-1 is a single, non-glycosylated, Polypeptide chain containing 159 amino acids and having a molecular mass of 18022 Dalton. Sequence: The sequence of the first five N-terminal amino acids was determined and was found to be Ser-Ala-Pro-Phe-Ser. Dimers and Aggregates: ≤ 1% as |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Interleukin 1 alpha, Recombinant, Human (IL-1a, Hematopoietin-1, Lymphocyte-activating Factor, LAF, Endogenous Pyrogen, Leukocyte Endogenous Mediator, LEM, Mononuclear Cell Factor, MCF) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | I7663A |
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| Order / More Info | Interleukin 1 alpha, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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