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| Product Name | Interleukin 1 alpha, Recombinant, Human |
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| Description | Purity ≥ 98% by SDS-PAGE and HPLC. Endotoxin: ≤ 0.1ng/ug (1EU/ug). IL-1alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine. Human IL-1alpha is a 18.0kD protein containing 159 amino acid residues. Biological Activity: The ED50 as determined by the dose-dependent stimulation of murine D10S cells is ≤ 0.001ng/ml, corresponding to a specific activity of ≥ 1x10e9u/mg. AA Sequence: SAPFSFLSN |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Interleukin 1 alpha, Recombinant, Human (IL-1a, Hematopoietin-1, Lymphocyte-activating Factor, LAF, Endogenous Pyrogen, Leukocyte Endogenous Mediator, LEM, Mononuclear Cell Factor, MCF) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | I7663 |
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| Order / More Info | Interleukin 1 alpha, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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