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| Product Name | LasA, Recombinant, Pseudomonas Aeruginosa, aa237-418, His-SUMO-Tag (Protease LasA) |
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| Description | Purity ~90% (SDS-PAGE). Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly-Gly-|-X substrates where X is Ala or Gly (PubMed:11179971). Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases (PubMed:2110137). Degradation of host elastin is likely to contribute to the pathogenicity of P.aeruginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in a given catalytic cycle, with the other stabilizing the catalytic intermediate. Source: Recombinant protein corresponding to aa237-418 from pseudomonas aeruginosa IasA, fused to His-SUMO-Tag at N-terminal expressed in E. coli. Molecular Weight: ~36.0kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Staphylolytic protease |
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| Gene, Accession, CAS # | SwissProt: P14789 |
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| Catalog # | 373987 |
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| Order / More Info | LasA, Recombinant, Pseudomonas Aeruginosa, aa237-418, His-SUMO-Tag (Protease LasA) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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