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| Product Name | Cathepsin B (CTSB) Inhibitor Screening BioAssay™ Kit (Fluorometric) |
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| Description | Cathepsin B (CTSB, EC 3.4.22.1) is a lysosomal cysteine proteinase that is suggested to participate in intracellular degradation and turnover of proteins. It has also been implicated in tumor invasion and metastasis. Intended Use: To screen, study and characterize potential inhibitors of Cathepsin B. Test Principle: Cathepsin B Inhibitor Screening BioAssay™ utilizes the ability of Cathepsin B to cleave the synthetic AFC based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin B-specific inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This simple and high-throughput adaptable assay kit can be used to screen/study/characterize the potential inhibitors of Cathepsin B. Kit Components: CTSB Reaction Buffer, 1x15ml ?CTSB Reagent, 1x100ul?Cathepsin B (human), 1x5ul?CTSB Substrate, Ac-RR-AFC, 10mM, 1x0.2ml?CTSB Inhi |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 219605 |
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| Order / More Info | Cathepsin B (CTSB) Inhibitor Screening BioAssay™ Kit (Fluorometric) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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