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Product Name | Human TGF alpha Carrier-Free Recombinant Protein |
Description | Human TGF alpha Carrier-Free Recombinant Protein, eBioscience™. Transforming growth factor (TGF) alpha is a 50-aa single-chain polypeptide derived from cleavage of transmembrane pro-TGF alpha. Sharing 42% identity with epidermal growth factor (EGF), TGF alpha binds the EGF receptor and activates downstream signaling pathways. TGF alpha is expressed by activated macrophages, keratinocytes, epithelial cells, and a variety of tumor-derived and transformed cell lines. This growth factor mediates cell proliferation and migration, as well as cellular transformation. Overexpression of TGF alpha has been linked to a variety of cancers, including the breast, colon, and stomach. |
Size | 100 µg |
Concentration | lyophilized |
Applications | Control: Assay-Dependent, Functional Assay: Assay-Dependent |
Other Names | n/a |
Gene, Accession, CAS # | Entrez: 7039; Uniprot: P01135 |
Catalog # | 34-8698-82 |
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Order / More Info | Human TGF alpha Carrier-Free Recombinant Protein from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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