产品名称 Visfatin, Recombinant, Human, His-Tag (PBEF, Pre-B Cell Colony-Enhancing Factor) from UNITED STATES BIOLOGICAL
产品货号 299563
产品价格 现货询价,电话:010-67529703
产品规格 5ug, 25ug
产品品牌 UNITED STATES BIOLOGICAL
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Product NameVisfatin, Recombinant, Human, His-Tag (PBEF, Pre-B Cell Colony-Enhancing Factor)
DescriptionPurity ~95% (RP-HPLC, SDS-PAGE). Visfatin, also known as pre-B cell colony-enhancing factor (PBEF), is a cytokine that is highly expressed in visceral fat and was originally isolated as a secreted factor that synergizes with IL-7 and stem cell factors to promote the growth of B cell precursors. Visfatin homologs have been identified in carp, invertebrate mollusks, and bacteria, as well as in vertebrates, including humans and the mouse. It has been postulated to play a role in innate immunity. Visfatin exerts insulin-mimetic effects that are dose-dependent and quantitatively similar to those of insulin in stimulating muscle and adipocyte glucose transport, and in inhibiting hepatocyte glucose production. Intravenous injection of recombinant visfatin in mice decreased plasma glucose in a dose-dependent fashion. In keeping with its insulin-mimetic effects, visfatin was as effective as insulin in reducing hyperglycemia in insulin-deficient diabetic mice. Visfatin was also found to be bound
Size5ug, 25ug
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Catalog #299563
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Order / More InfoVisfatin, Recombinant, Human, His-Tag (PBEF, Pre-B Cell Colony-Enhancing Factor) from UNITED STATES BIOLOGICAL
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