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| Product Name | Telomerase, Human, Control Peptide |
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| Description | Highly purified. A 16aa Peptide sequence mapping in the middle of human Est2 (1) was selected for antibody production. The peptide was coupled to KLH. The 3'ends of chromosomes are capped with telomere sequences (TTAGGG; 6-26 nucleotides in length) by ribonucleoprotein telomerase during DNA replication. Telomerase is an unusual RNA-dependent DNA polymerase that uses and RNA component to specify the addition of telomere. The telomeric RNA contains a sequence complementary to TTAGGG. In ciliated protozoa and yeast, telomere length is maintained by regulating the activity of telomerase. Many mammalian cells do not express telomerase resulting into shortening of telomere with each cell division, and ultimately causing the chromosomal instability, aging and cell death. Approx. 4.8 kb of telomeric DNA is lost with each cell division resulting into large number of chromosomal abnormalities. Most recently, introduction of telomerase into normal human cells has been shown to extend normal cell |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | Telomerase, Human, Control Peptide (EST2, hEST2, TCS1, Telomerase Catalytic Subunit, Telomerase-associated protein 2, Telomere Reverse Transcriptase, TERT, TP2, TRT) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | T2399-15 |
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| Order / More Info | Telomerase, Human, Control Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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