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| Product Name | TNFRSF12A, Recombinant, Human |
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| Description | Purity ~98% (SDS-PAGE and HPLC). TWEAKR belongs to the TNF family of transmembrane proteins and contains a cytoplasmic death domain, which can activated the cell's apoptotic machinery. It is expressed in the spleen, thymus, peripheral blood lymphocytes, colon, and small intestine. Signal transduction by TWEAKR can be activated by either the membrane anchored or the soluble TWEAK. Recombinant soluble TWEAKR is a 53aa polypeptide, 5.6kD, comprising the entire extracellular domain of the full length TWEAKR protein. Source: Recombinant protein corresponding to human TWEAK Receptor, expressed in E.coli. Biological Activity: Determined by its ability to inhibit TWEAK-induced weak cell death of HT29 cells. The expected ED50 for this effect is 1-3ug/ml. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: EQAPGTAPCS RGSSWSADLD KCMDCASCRA RPHSDFCLGC AAAPPAPFRL LWP |
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| Size | 5ug, 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TNFRSF12A, Recombinant, Human (Tumor Necrosis Factor Receptor Superfamily Member 12A, CD266, Fibroblast Growth Factor-inducible Immediate-early Response Protein 14, FGF-inducible 14, FN14, Tweak-receptor, TweakR) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149656 |
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| Order / More Info | TNFRSF12A, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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