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| Product Name | TNFRSF1A, Recombinant, Human, aa31-210, GST-Tag (Tumor Necrosis Factor Receptor Superfamily Member 1A) |
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| Description | Purity ~90% (SDS-PAGE). Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. Source: Recombinant protein corresponding to aa31-210 from human TNFRSF1A, fused to GST-Tag at N-terminal expressed in E. coli. Molecular Weight: ~47.2kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Tumor necrosis factor receptor 1, TNF-R1 Tumor necrosis factor receptor type I, TNF-RI, TNFR-Ip55p60, CD120a |
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| Gene, Accession, CAS # | SwissProt: P19438 |
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| Catalog # | 375622 |
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| Order / More Info | TNFRSF1A, Recombinant, Human, aa31-210, GST-Tag (Tumor Necrosis Factor Receptor Superfamily Member 1A) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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