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| Product Name | TNFRSF1A, Recombinant, Human, aa22-211, His-Tag |
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| Description | Purity ~85% (SDS-PAGE). TNFRSF1A is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. Source: Recombinant protein corresponding to aa22-211 from human TNFRSF1A, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~23.6kD (213aa) Applications: Suitable for use in SDS-PAGE. |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | TNFRSF1A, Recombinant, Human, aa22-211, His-Tag (Tumor Necrosis Factor Receptor Superfamily Member 1A) |
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| Gene, Accession, CAS # | Accession: NP_001056 |
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| Catalog # | 218638 |
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| Order / More Info | TNFRSF1A, Recombinant, Human, aa22-211, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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