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Product Name | Ubiquitin-AMC |
Description | Prepared by the C-terminal derivatisation of ubiquitin with 7-amino-4-methylcoumarin. Acts as a useful and sensitive fluorogenic substrate for a wide range of deubiquitinylating enzymes (DUBs), including ubiquitin C-terminal hydrolases (UCHs) and ubiquitin specific proteases (USPs). Ubiquitin-AMC has been shown to be a sensitive substrate for UCH-L3 (Km = 0.039µM) and for Isopeptidase-T (Km = 0.17-1.4µM), as well as for studying deubiquitinylating activity where detection sensitivity or continuous monitoring of activity is essential. MW: 8.6 Kda. Purity ≥95% |
Size | 25 µg |
Concentration | 1 mg/ml (DMSO) |
Applications | RUO |
Other Names | Ubiquitin-Aminomethylcoumarin |
Gene, Accession, CAS # | n/a |
Catalog # | 4842-25 |
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Order / More Info | Ubiquitin-AMC from BIOVISION, INC. |
Product Specific References | n/a |
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