产品详情 |
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Product Name | MK-8745 |
Description | An Aurora A kinase inhibitor (IC50 = 0.6 nM); selective for Aurora A over Aurora B kinase (IC50 = 280 nM); induces cell cycle arrest at the G2/M phase in non-Hodgkin lymphoma cells at 1 µM; induces apoptosis and polyploidy in p53-positive and -negative HCT116 colon cancer cells, respectively, at 5 µM; induces apoptosis in sarcoma, melanoma, and pancreatic cancer cell lines in a p53-dependent manner at 5 µM |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 885325-71-3 |
Catalog # | 26190-25 |
Price | |
Order / More Info | MK-8745 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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