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Product Name | MART-1/Melan-A, mouse recombinant |
Description | MART-1 (also known as Melan-A) is a melanocyte differentiation antigen or marker recognized by autologous cytotoxic T lymphocytes. It is a membrane protein with one transmembrane peptide. Melan-A is expressed by a large proportion of melanoma tumors, both melanotic and amelanotic and by melanoma cell lines. It is present in melanocytes of normal skin and retina, nevi and in more than 85% of melanomas. Melan-A/MART-1 is not expressed by non-melanoma malignancies. It is recognized by autologous cytotoxic T lymphocytes. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. Six other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, Tyrosinase, gp100, gp75, BAGE-1, |
Size | 50 µg |
Concentration | n/a |
Applications | RUO |
Other Names | Melanoma antigen recognized by T-cells 1, Antigen LB39-AA, Antigen SK29-AA, MART-1, Melan-A |
Gene, Accession, CAS # | Melan-A, Gene ID: 77836, Accession: Q2TA50 |
Catalog # | 4824-50 |
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Order / More Info | MART-1/Melan-A, mouse recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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