| 产品详情 |
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| Antigenic Specificity | HPA-5b |
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| Clone | F2H11 |
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| Host Species | Human |
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| Reactive Species | human |
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| Isotype | IgG1k |
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| Format | purified |
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| Size | 100µg/50µg |
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| Concentration | n/a |
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| Applications | Platelet phenotyping by flow cytometry, IF, ELISA, platelet aggregation studies |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Neonatal AlloImmune Thrombocytopenia (NAIT) is the commonest cause of severe isolated thrombocytopenia in the foetus and newborn. In Caucasians, 97% of NAIT are caused by HPA-1a or HPA-5b alloantibodies. By combining CD40 activation and Epstein-Barr virus transformation of B cells isolated from a woman with high titre of anti -HPA-5b alloantibodies. F2H11 human monoclonal antibody is highly specific (does not bind to HPA5a) , and allows a rapid and accurate phenotyping of pregnant women as well as selection of blood donors. (Merieux Y, Rigal D, Pin JJ, XVIIth Regional Congress, International Society of Blood Transfusion, Madrid 2007 ; Guillot-Chene P, Lebecque S, Rigal D, Annales Pharmaceutiques Francaises, 06/2009, 67 (3) 182-6). |
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| Immunogen | n/a |
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| Other Names | GPIa-IIa |
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| Gene, Accession # | n/a |
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| Catalog # | DDX9021 |
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| Price | |
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| Order / More Info | HPA-5b Antibody from DENDRITICS SAS |
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| Product Specific References | n/a |
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