产品名称 Neuropilin Antibody from DENDRITICS SAS
产品货号 DDX0440
产品价格 现货询价,电话:010-67529703
产品规格 100µg/50µg
产品品牌 DENDRITICS SAS
产品概述
产品详情
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Antigenic SpecificityNeuropilin
Clone211H6.01
Host SpeciesMouse
Reactive Specieshuman, dog, swine
IsotypeIgG1
Formatpurified
Size100µg/50µg
Concentrationn/a
ApplicationsFACS, IHC, IP
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DescriptionWe have generated a mAb that identifies human pDCs ex vivo. In blood, 211H6 antigen is highly expressed on IL3Ralpha+ BDCA-2+ CD11c- pDCs. It does not stain lymphocytes, monocytes, basophils and granulocytes. In vitro it is also expressed on monocyte-derived DCs. Upon maturtaion in IL-3 and CD40-L, or with influenza virus, 211H6 is maintained at the cell surface. In situ 211H6 recognizes some isolated cells in T cell zones of tonsils, lymphatic vessels and high endothelial venules. THe 211H6 antigen has been identified as BDCA-4. Neuropilin-1 is a membrane-bound co-receptor to a tyrosine kinase receptor for both vascular endothelial growth factor (VEGF) and semaphorin (SEMA3A) family members. Neuropilin 1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration and invasion. (Dzionek A and al., 2000 J. Immunol., 165: 6037-6046)
Immunogenn/a
Other NamesBlood Dendritic Cell Antigen 4 protein
Gene, Accession #n/a
Catalog #DDX0440
Price
Order / More InfoNeuropilin Antibody from DENDRITICS SAS
Product Specific Referencesn/a
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