| 产品详情 |
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| Antigenic Specificity | CD273 (B7-DC, PD-L2) |
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| Clone | MIH18 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, κ |
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| Format | biotin conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FC), IHC, Immunofluorescence Microscopy (IF) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Biotin anti-human CD273 (B7-DC, PD-L2). CD273, known as B7-DC, is also called programmed death ligand 2 (PDL2). This ligand is a 25 kD type I transmembrane protein and a member of B7 family within the immunoglobulin receptor superfamily and is expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions. Clone MIH18 is reported to block PDL2. |
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| Immunogen | Human B7-DC transfected cells |
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| Other Names | B7-DC, PD-L2, PDL2, B7DC |
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| Gene, Accession # | Gene ID: 80380 |
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| Catalog # | 345510 |
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| Price | |
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| Order / More Info | CD273 (B7-DC, PD-L2) Antibody from BIOLEGEND |
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| Product Specific References | PubMed: 24714771 |
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