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Product Name | PD-1/PDCD1, Human Recombinant |
Description | Programmed death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon treatment with IFN-γ. PD-L2 expression is more restricted and is expressed mainly by DCs and a few tumor lines. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activatio |
Size | 50 µg |
Concentration | n/a |
Applications | RUO |
Other Names | PDCD1, PD1, CD279, SLEB2, hPD-1, hPD-l |
Gene, Accession, CAS # | PDCD1, Gene ID: 5133, Accession: Q15116 |
Catalog # | P1024-50 |
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Order / More Info | PD-1/PDCD1, Human Recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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