| 产品详情 |
| Edit |   |
|---|
| Product Name | MM-102 |
|---|
| Description | A WDR5/MLL interaction inhibitor (IC50 = 2.4 nM) that blocks MLL1 methyltransferase activity, reducing the expression of HoxA9 and Meis-1 genes, which are both critical MLL1 target genes in MLL1 fusion protein-mediated leukemogenesis; inhibits cell growth and induces apoptosis in leukemia cells harboring MLL1 fusion proteins |
|---|
| Size | 5 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | peptidomimetic MLL1 mixed lineage leukemia 1 WDR5 WD repeat-containing protein 5 inhibitor inhibit biochemical WD-repeat mixed-lineage MLL methyltransferase epigenetics interaction WDR5/MLL gene regulation histone modification chromatin research |
|---|
| Gene, Accession, CAS # | CAS: 1417329-24-8 |
|---|
| Catalog # | 17699-5 |
|---|
| Price | |
|---|
| Order / More Info | MM-102 from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|