| 产品详情 |
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| Antigenic Specificity | IL-21 |
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| Clone | 3A3-N2 |
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| Host Species | Mouse |
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| Reactive Species | human, cross-reactivity: rhesus |
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| Isotype | IgG1, κ |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | ELISA Capture |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Purified anti-human IL-21. Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases. |
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| Immunogen | Recombinant full length human IL-21 |
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| Other Names | Interleukin 21 |
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| Gene, Accession # | Gene ID: 59067 |
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| Catalog # | 513001 |
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| Price | |
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| Order / More Info | IL-21 Antibody from BIOLEGEND |
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| Product Specific References | n/a |
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| 产品资料 |
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