| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | EOS |
|---|
| Clone | W15169A |
|---|
| Host Species | Mouse |
|---|
| Reactive Species | human |
|---|
| Isotype | IgG1, κ |
|---|
| Format | purified |
|---|
| Size | 100 µg |
|---|
| Concentration | n/a |
|---|
| Applications | Western Blot (WB) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Purified anti-EOS. EOS, also known as IKZF4 (Ikaros family zinc finger 4), is a member of the Ikaros family of zinc finger transcription factors, which are key transcriptional repressors during development of lymphocytes. Each of the five Ikaros family members (Ikaros, Helios, Aiolos, Eos and Pegasus) has N-terminal and C-terminal zinc-finger motifs responsible for DNA binding and dimerization, respectively. EOS is a highly conserved DNA-binding protein that recognizes the typical 5'WGGAAT-3' Ikaros-binding sequence. EOS has been implicated in the development of lymphoid cells and nervous systems, as well as mediating FOXP3-dependent gene silencing in CD4+ regulatory T cells though interacting with FOXP3 and CTBP1. |
|---|
| Immunogen | Partial human EOS recombinant protein (271-520 a.a.) expressed in E. coli. |
|---|
| Other Names | Ikaros family zinc finger protein 4 (IKZF4), KIAA1782, ZNFN1A4 |
|---|
| Gene, Accession # | Gene ID: 64375 |
|---|
| Catalog # | 695302 |
|---|
| Price | |
|---|
| Order / More Info | EOS Antibody from BIOLEGEND |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|