| 产品详情 |
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| Product Name | ITD-1 |
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| Description | ITD-1 is a potent and highly selective TGFβ pathway inhibitor (IC50 = 0.85 µM). ITD-1 promotes cardiomyocyte differentiation specifically via degradation of the TGFβ type II receptor (TGFBR2), effectively clearing the receptor from the cell surface and selectively inhibiting intracellular signaling (IC50 = 0.4-0.8 µM), revealing a role for TGFβ signaling mechanism as a repressor of cardiomyocyte fate. ITD-1 does not induce differentiation of vascular smooth muscle cells or endothelial cells. MW: 415.52. Purity ≥98% by HPLC |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[1,1'-Biphenyl]-4-yl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxo-3-quinolinecarboxylic acid ethyl ester |
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| Gene, Accession, CAS # | CAS: 1099644-42-4 |
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| Catalog # | 2879-10 |
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| Price | |
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| Order / More Info | ITD-1 from BIOVISION, INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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