产品详情 |
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Antigenic Specificity | CD44 |
Clone | IM7 |
Host Species | Rat |
Reactive Species | mouse, human, cross-reactivity: chimpanzee, baboon, cynomolgus, rhesus, squirrel monkey, horse , cow, porcine, dog , cat |
Isotype | IgG2b, κ |
Format | purified, azide-free |
Size | 1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC), CyTOF®, ELISA, IHC, IP, CMCD, Stim |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ultra-LEAF™ Purified anti-mouse/human CD44. CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation. |
Immunogen | Dexamethasone-induced myeloid leukemia M1 cells |
Other Names | Hermes, Pgp-1, H-CAM, HUTCH-1, ECMR III, gp85, Ly-24 |
Gene, Accession # | Gene ID: 12505, 960 |
Catalog # | 103046 |
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Order / More Info | CD44 Antibody from BIOLEGEND |
Product Specific References | PubMed: 15899824,15905539,15972696,17804689,18003887,18045971,19584402,19849846,21062915,24481605,25776075 |
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