产品详情 |
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Antigenic Specificity | TPR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 µl |
Concentration | n/a |
Applications | Western blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TPR Antibody. The vertebrate nuclear pore complex (NPC) is a macromolecular assembly of protein subcomplexes forming a structure of eightfold radial symmetry. The NPC core consists of globular subunits sandwiched between two coaxial ring-like structures of which the ring facing the nuclear interior is capped by a fibrous structure called the nuclear basket. The assembly of the NPC is a stepwise process in which Trp-containing peripheral structures assemble after other components, including p62. TPR localizes to intranuclear filaments of the NPC, and is a component of the cytoplasmic fibrils of the NPC implicated in nuclear protein import. Experimental data suggest that TPR is tethered to intranuclear filaments of the NPC by its coiled coil |
Immunogen | Synthetic peptide of human TPR |
Other Names | TPR, Translocated Promoter Region |
Gene, Accession # | Gene ID: 7175, Accession: NP_003283.1 |
Catalog # | 3781-100 |
Price | |
Order / More Info | TPR Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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