产品详情 |
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Antigenic Specificity | MMP-3 |
Clone | F36P1B4 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), IHC, ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-MMP3. Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances withinthe extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP1 cleaves collagens of types I, II, III, VII and X.MMP1 is thought to play an important role in rheumatoid and osteo-arthritis pathogenesis as mediators of cartilage and bone destruction. Clone F15P3B6 has been shown to be useful for western blotting and immunohistochemistry of human MMP1. |
Immunogen | Ovalbumin-conjugated synthetic peptide CKSLRKLEPELH |
Other Names | Progelatinase, STR1, Transin, Stromelysin I |
Gene, Accession # | Gene ID: 4314 |
Catalog # | 634902 |
Price | |
Order / More Info | MMP-3 Antibody from BIOLEGEND |
Product Specific References | PubMed: 21554870 |
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