产品详情 |
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Product Name | GNE-0877 |
Description | A selective, brain-penetrable LRRK2 inhibitor (Ki = 0.7 nM); inhibits LRRK2 Ser1292 autophosphorylation in BAC transgenic mice expressing human LRRK2 protein with the G2019S Parkinson's disease mutation (IC50 = 3 nM in vivo) |
Size | 500 µg |
Concentration | n/a |
Applications | n/a |
Other Names | neuroscience Leucine-rich repeat kinase 2 LRRK2 inhibitor Parkinson's disease mutation biochemical inhibit selective GNE0877 brain-penetrable Ser1292 Ser 1292 autophosphorylation protein G2019S in vivo |
Gene, Accession, CAS # | CAS: 1374828-69-9 |
Catalog # | 16251-500 |
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Order / More Info | GNE-0877 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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