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Product Name | PPM1F, 1-454aa, Human, His tag, E.coli |
Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT.. PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. Recombinant human PPM1F protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Size | 0.5mg, 100ug, 20ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Protein phosphatase 1F, CAMKP, CaMKPase, FEM-2, hFEM-2, POPX2 |
Gene, Accession, CAS # | NP 055449 |
Catalog # | ATGP2281 |
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Order / More Info | PPM1F, 1-454aa, Human, His tag, E.coli from ATGen |
Product Specific References | n/a |
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