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Product Name | Ascomycin |
Description | Analog of FK 506 (Cat. No. 3631); binds to FK 506-binding protein 12 (FKBP12) in order to inhibit calcineurin phosphatase activity (IC50 = 49 nM) and activation of nuclear factor of activated T cells (NFAT). Displays antifungal and immunosuppressive activities. MW (observed): 792.01. |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-py. FK 520, FR 900520 |
Gene, Accession, CAS # | CAS: 104987-12-4 |
Catalog # | 4210/1 |
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Order / More Info | Ascomycin from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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