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| Product Name | 4-octyl Itaconate |
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| Description | A prodrug form of itaconate; hydrolyzed to itaconate by esterases in C2C12 cells and LPS-activated mouse macrophages; increases Nrf2 protein levels and expression of Nrf2 target genes and enhances LPS-induced Nrf2 stabilization in mouse macrophages; decreases serum levels of IL-1β and TNF-α, increases Nrf2 protein expression, and protects against LPS-induced lethality in wild-type, but not Nrf2 knockout, mice at 50 mg/kg |
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| Size | 250 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Octylitaconate 4-OI 4OI C2C-12 lipopolysaccharide Nrf-2 IL1β TNFα |
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| Gene, Accession, CAS # | CAS: 3133-16-2 |
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| Catalog # | 25374-250 |
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| Order / More Info | 4-octyl Itaconate from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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