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| Antigenic Specificity | Toxoplasma Gondii Antigen |
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| Clone | To5T |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | ion exchange purified, no preservative |
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| Size | 1 mg |
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| Concentration | 1.0mg/mL |
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| Applications | ELISA. Anti-Human Toxoplasma Gondii Antigen Antibody has been tested in ELISA. Can be used as the tracer antibody in conjunction with Anti-Human IgM Capture (MOUSE) Antibodies (p/n 200-301-ME1) as the coating antibody. May be useful in multiple assays. Specific conditions for reactivity should be optimized by the end user. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This purified monoclonal antibody is directed against Human Toxoplasma Gondii Antigen and is purified by Ion exchange chromatography. Purity is confirmed by ELISA >95% pure. Toxoplasma gondii is an intracellular parasitic alveolate that causes the disease toxoplasmosis. Found worldwide, T. gondii is capable of infecting virtually all warm-blooded animals, but felids such as domestic cats are the only known definitive hosts in which the parasite may undergo sexual reproduction. Initially, a T. gondii infection stimulates production of IL-2 and IFN-γ by the innate immune system. Continuous IFN-γ production is necessary for control of both acute and chronic T. gondii infection. These two cytokines elicit a CD4+ and CD8+ T-cell mediated immune response. Thus, T-cells play a central role in immunity against Toxoplasma infection. T-cells recognize Toxoplasma antigens that are presented to them by the body's own Major Histocompatibility Complex (MHC) molecules. The specific genetic sequence of a given MHC molecule differs dramatically between individuals, which is why these molecules are involved in transplant rejection. Individuals carrying certain genetic sequences of MHC molecules are much more likely to be infected with Toxoplasma. Immune pressure eventually leads the parasite to form cysts that normally are deposited in the muscles and in the brain of the hosts. Anti-Human Toxoplasma Gondii Antigen Antibody is useful for researchers interested in infectious disease. |
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| Immunogen | Mouse monoclonal Anti-Human Toxoplasma Gondii Antigen Antibody was produced in mice by repeated immunizations with Toxoplasma Gondii lysate. |
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| Other Names | Mouse Anti-Human Toxoplasma Gondii Antigen Antibody, Mouse Anti-Toxoplasma Gondii Antigen Antibody |
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| Gene, Accession # | Gene ID: 6647, UniProt: P00441, NCBI: NP 000445.1 |
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| Catalog # | 200-301-ME4 |
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| Price | |
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| Order / More Info | Toxoplasma Gondii Antigen Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | n/a |
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