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Product Name | NEIL2, 1-332aa, Human, His tag, E.coli |
Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl . Endonuclease 8-like 2, also known as NEIL2, belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction. It has negligible or undetectable activity with 8-oxoguanine, thymine glycol, 2-hydroxyadenine, hypoxanthine, and xanthine. Recombinant human NEIL2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Size | 250ug, 50ug, 10ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Endonuclease 8-like 2, NEH2, NEI2, Nei-like protein 2 |
Gene, Accession, CAS # | NP 659480 |
Catalog # | ATGP1526 |
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Order / More Info | NEIL2, 1-332aa, Human, His tag, E.coli from ATGen |
Product Specific References | n/a |
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