产品详情 |
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Product Name | OC000459 |
Description | A potent, selective DP2 antagonist (Kis = 13, 3, and 4 nM for human recombinant DP2, rat recombinant DP2 receptors, and human native DP2 from Th2 cell membranes, respectivley); inhibits chemotaxis and cytokine production of human Th2 lymphocytes with IC50 values of 28 and 19 nM, respectively; inhibits eosinophilia in rats and guinea pigs (ED50s = 0.04 and 0.01 mg/kg, respectively) |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | antagonists DP2 receptors chemotaxis cytokines production asthma airway eosinophilia inhibitors CRTH2 inhibits inhibitions OC-000459 OCs 000459 459 potent selective prostaglandins PGs PGD2 Th2 lymphocytes bloods eosinophilia 13,14-dihydro-15-keto-PGD2 |
Gene, Accession, CAS # | CAS: 851723-84-7 |
Catalog # | 12027-5 |
Price | |
Order / More Info | OC000459 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |
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