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| Product Name | Lonafarnib |
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| Description | Potent farnesyl transferase inhibitor (IC50 = 1.9 nM). Inhibits farnesylation of RAS. Also inhibits Pgp transport (IC50 < 3 μM) and increases potency and anticancer activity when used in conjunction with cytotoxic Pgp substrates. Inhibits neovascularization by affecting cell motility. Orally bioavailable. Purity 98%. MW (observed): 638.82 |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[2-[4-[(11R)-3,10-Dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]-1-piperidinyl]-2-oxoethyl]-1-piperidinecarboxamide |
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| Gene, Accession, CAS # | CAS: 193275-84-2 |
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| Catalog # | 6265/10 |
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| Price | |
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| Order / More Info | Lonafarnib from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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